Reply to Gibran and Kapoor

Reply to the letter by Kapoor entitled 'Emerging new markers of stroke risk and prognosis'.

to be elevated in patients with acute ischemic stroke [2–6] , in particular, those with atrial fibrillation [2–4, 6] , and associated with neurological severity [3–5] . Furthermore, we demonstrated that high BNP level is associated with in-hospital mortality [5] or long-term mortality [2] after ischemic stroke. Recently, a rapid (approx. 15 min) and easy assay for the measurement of BNP was dev...

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Intracellular parasites manipulate host cell apoptosis in different ways either to increase their life span within infected cells or to spread infection. The present data provided information on the cellular changes taking place in spleen and peripheral blood during Plasmodium berghei-infection and indicated apoptosis mediated host immune response during infection. Our results suggested a signi...

Tarun Kapoor: In the right position to study chromosomes

JCB • VOLUME 187 • NUMBER 6 • 2009 754 P roperly positioning a cell’s chromosomes at the center of the mitotic spindle is a tricky business. Errors or failures in spindle attachment can cause chromosome mis-segregation, leading to cell death or to cancer. Scientists are fi nally starting to get a handle on this problem, thanks in part to the work of Tarun Kapoor. Kapoor approaches cell biology ...

Kapoor and Subbarao: Formulation Development and Characterization of Itraconazole Granules

Itraconazole is practically insoluble in water; large interindividual and intra-individual variations of its oral bioavailability are reported. The main purpose of this study was to prepare and evaluate itraconazole granules for immediate release as drug delivery formulations. As a part of formulation optimization, different concentrations of hydroxypropyl-methyl cellulose (HPMC) E5 were taken ...

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